Lorre, Aronsohn, and Medelsohn on whether they learned anything about their shows, having someone else come in and work on them:

CHUCK: The biggest challenge for us was doing a comedy with a murder in it. I mean, generally our stories are a little lighter.

LEE: Our characters usually don’t have to react to corpses.

CHUCK: And that was the big leap, will the audience go with us, with a dead body in the show and a forensic examination of a dead body in our show. There was a moment there where it could’ve gone either, but I think the results are spectacular, it’s a really funny episode.

CAROL: I think also we all had to deal with issues of control. We’re all used to being in control and in charge of our shows and even though this was a freelance type of situation, we freelanced on Two and a Half Men, Chuck and Lee freelanced on CSI, there was an expectation and also a desire on all of our parts to have a true collaboration. You know you have to give a little, it’s sort of a life lesson I think.

Naren Shankar, Carol Mendelsohn, Lee Aronsohn, and Chuck Lorre on the reactions of the cast members of both shows when they first heard of the crossovers:

NAREN SHANKAR: Billy Peterson, "Are you crazy?"

CAROL: And, "I’m not crossing over."

LEE: Charlie Sheen, "Are you serious?"

CHUCK: Eyebrows were raised. Then we told them that the writing was crossing over not the acting, then the eyebrows raised a little higher.

CAROL: Naren and I told Billy that he would get what he had never gotten before, a script written by two Emmy winning writers.

LEE: Nominated. We didn’t win Carol, you lied to him. We never won [laughs].

CAROL: But then I decided not to tell him that.

How much of your real life experience did you draw on writing scenes since in the CSI episode is the behind the scenes of this fictional sitcom called Annabelle?

CHUCK: This is entirely an act of fiction.

LEE: We made it all up.

CHUCK: The entire thing here is imagination. Working with these kinds of people is a joy [laughs] - the horror of writing and producing a TV sitcom for a female star, that’s just a stretch of the imagination.

LEE: Yeah, it actually never invokes a murderous rage.

Chuck Lorre on if this the first time there’s been a crossover episode between a comedy and a drama:

"And it very well may be the last one. I mean they did once, I remember, and I don’t think it was writers. On Cheers some doctors from St. Elsewhere showed up at the bar, and that’s the only intersection I can remember."

Lee Aronsohn on whether they went over each other’s scripts to give helpful suggestions:

"A lot. After they pitched, they did an outline of our show, we did an outline of their show. Then they did a first draft of our show and we did a first draft of their show and we all got together and punched up and they gave us the forensics and the plotting of the crimes and we kind of put in our hahas. We put in our brilliant comedy."